bitter, slightly cold
Enters: Liver, Spleen
Actions: Kills parasites (lice and various intestinal parasites, including hookworms, roundworms, tapeworms, pinworms); clears heat; eliminates toxicity; cools the blood; stops bleeding (charred).
Indications:
• Heat in the blood: rashes, eruptions, epistaxis, hematemesis, hemafecia, and especially uterine bleeding. The herb should be charred when used to stop bleeding.
• Heat and toxicity: mumps, epidemic disease, sores.
• Wind-heat EPI.
• Also for alopecia, head sores.
• Antiviral: influenza. Dryopteris (Dong bei guan zhong) has been taken as a preventive measure during flu epidemics. Currently used as a preventative in formulas for corona virus.
• Stimulates contraction of uterus. Used in post-partum, post-miscarriage, and post-surgical uterine bleeding.
• Do not take with fatty food: one toxic component (filmarone) is usually not absorbed from the GI tract unless the herb is taken with a very fatty meal.
John Christopher: Anthelmintic (taeniafuge, vermifuge), astringent, tonic, vulnerary.
• Tapeworms, roundworms, seat worms, pinworms.
• Wounds, rickets.
Dose: 6-15g
Anti-Influenza Virus (H5N1) Activity Screening on the Phloroglucinols from Rhizomes of Dryopteris crassirhizoma. Abstract
For screening the active phloroglucinols on influenza virus (H5N1) from Dryopteris crassirhizoma NaKai, a database was established including twenty-three phloroglucinols that had been isolated from Dryopteris crassirhizoma. Their inhibitory effect on the neuraminidase (NA) of influenza virus H5N1 was screened by molecular docking. As a result, three candidates were selected. The rhizomes of D. crassirhizoma were subjected to isolation and purification processes to obtain the inhibitor candidates. Thirteen phloroglucinols were obtained, including three selected candidates and two new phloroglucinols. The five phloroglucinols were investigated for their inhibitory activity on NA in vitro. The results showed that dryocrassin ABBA and filixic acid ABA exhibited inhibitory effects on NA with IC50 as 18.59 ± 4.53 and 29.57 ± 2.48 ?M, respectively, and the other three phloroglucinols showed moderate inhibitory activity. Moreover, the anti-influenza virus (H5N1) activity and cytotoxicity of dryocrassin ABBA and filixic acid ABA were tested on Madin-Darby canine kidney (MDCK) cells with the cell counting kit-8 (CCK8) method. The results confirmed that dryocrassin ABBA exhibited an inhibitory activity with low cytotoxicity (TC50 > 400 ?M) against influenza virus (H5N1) which will have to be investigated in further detail. In conclusion, phloroglucinols from D. crassirhizoma were shown to have anti-influenza virus activity, and especially dryocrassin ABBA, one of the phloroglucinols, may have the potential to control influenza virus (H5N1) infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103729/